Mouse Models and the Genetics of Nicotine Dependence
نویسندگان
چکیده
Detailed studies of inbred mouse strains have provided remarkable insights into how genetics shape complex processes, ranging from cancer susceptibility to immunity. The mouse models of response to addictive substances such as nicotine are now showing similar promise for revealing the underlying complex genetics and physiological mechanisms contributing to dependence. This chapter examines key issues in using mouse models for nicotine dependence, including
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